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  1. #1
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    Working out MU for a Blood Group???

    From discussions with colleagues across UK it appears that very much time and effort is being placed into working out the MU for a blood group result. My questions are:
    1. What is the purpose of identifying MU for a blood group?
    2. A blood group is a qualitative test not quantitative, so wouldn't MU be irrelevent?
    3. If an MU is required, how do you calculate/ factor in sampling errors from the clinical areas to address wrong blood in tube errors?
    4. If an MU is needed- will this be stated in the User Manual? If not, why not?
    5. How would an MU be written on a report or in the User Manual- eg Patient is group A+ ( or there is a X % chance they may not be ???!)
    6. What is the clinical significance of working out the MU for this test? Is this actually going to give anyone ( clinicians/ staff/ patients) confidence in the process?

    I'm often wrong about things, but really want to understand WHY this is required ? Again, are we ALL misinterpreting the clauses/ NCs etc and creating more unnecessary work within the labs , many of who are already under staffing capacity and can't get important basic improvement tasks done?

    Some clarification would be helpful.

    Many thanks
    Rashmi

  2. #2
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    Also , majority of patients are tested twice!!on separate samples
    dont start me on this one!

  3. #3
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    Thanks EClarke- I know how you feel!

    To continue this saga, and thanks to colleagues for forwarding me their spreadsheets on calculations, though I still havenít been told WHY itís being done.

    I understand that analysers create data/ numbers from the visual images of each individual reagent; this data is either interpreted into a recognized blood group or not depending on the reaction strength rules (0,1+to 4+) applied.

    Some questions:
    1. If MU is needed, whenever the analyser camera is re-calibrated / changed/ software updated/ or annually, will you re-calculate?
    2. How do Westgard rules apply to blood grouping? (For antibody screening, we can apply this rule based on the weak antibody controls run. We use 3+ reaction required +/-1 strength, anything outside follows out of spec testing protocols).
    3. How do you apply MU for a manual group- or is this exempt? This testing probably has a higher error rate than automation.

    I will not be working MU for this test, as far as I can make sense, my test is controlled by our ABO/D reagent controls, and analyser settings ensure that only certain reaction strengths are interpreted and these are checked, ( eg for our D typing potentiated reagents the analysers are set to interpret 0= RhD-Neg and 4+ as RhD Pos , anything less is rejected, so we donít miss the weak-Ds for reflex testing).

    My point isÖÖ There is so much time being needlessly wasted across 300+ labs and no guidance given, or if given, is inconsistent.

    Some thoughts/hints:
    1. The best assessors/ inspectors always guide staff on approaches to address NCs, keeping it as simple as possible. Try to teach, not confuse please!
    2. Some formal and consistent guidance is needed across UK- how about posting on this Forum?
    3. Standard terminology would also be helpful.

    Many thanks
    Last edited by Rashmi; 8th Aug 2019 at 11:38 PM.

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