What key SOPs that should be in place to manage Clinical Trials conducted by CRO?

[pharmavenky]

I am interested to know what SOPs would you consider to be essential to govern the management (sponsor responsibilities) of Clinical Trials in which the activities are essentially outsourced by a company to a CRO?

I believe SOPs pertaining to Investigational products, ethics committee and study related procedure- site initiation, feasibility and sample transfer,collection are the most imporatnat accordng to me the most imporatnt SOPS