I would appreciate your thoughts as to when it is most appropriate for the below to be signed onto the sponsor delegation log.

1. the eCRF/ ePRO creator and
2. eCRF/ ePRO capture systems staff

I had thought at early stages during design/ annotation but have heard others say once trial is open.

Also, the ePROs are annotated for a 3rd party ePRO provider - does the provider need to be on the sp. delegation log or can that be covered by the sponsor staff dealing with the ePRO annotations and UAT?

Thank you,