Strange. Pre-dating sounds like an non-GCP Compliant process. Surely the delegated party may well resign from the trial or be determined by the PI that they are no longer GCP compliant and have their duties removed from them, before the theoretical end date.
From a GCP Compliance point of view pre- or post dating anything is open to falsification or fraud. Its almost like a pre-signed financial "blank Cheque", where it can be used at anytime without further authorisation. Signature dates should be contemporaneous so that we know when authorisation has been given, and when authorisation has been withdrawn. It is crazy to assume that once delegation authorisation has been granted that it may not be withdrawn at anytime in the future!

Good idea to read ALL of the things that have been written in this Thread below.

The PI must understand that they are personally responsible for all tasks that they do not delegate in advance. They are also responsible for oversight of all those they have delegated tasks to. The FDA ten point plan for PI oversight says that they should document this oversight!


You should look at the other sections of this MHRA forum -- for instance; PI delegating PI duties; Delegation of duties.