The ICH press release of 17 Nov 2016 stated that :- "Global good clinical practice (GCP) guideline amendment adopted. The 1996 ICH guideline on GCP is one of the most significant achievements of the ICH process, establishing harmonised standards for clinical trials. The ICH Assembly adopted an important amendment (ICH E6(R2)) that aims to encourage sponsors to implement improved oversight and management of clinical trials, while continuing to ensure protection of human subjects participating in trials and clinical trial data integrity. This amendment will now be implemented by ICH members through national and regional guidance".

However the ICH website for E6 still (as of 29 Nov 2016) have only the draft Step 2b available and not yet the final step 4 version.